SAB4500465
Anti-CRHR1 antibody produced in rabbit
affinity isolated antibody
Synonym(s):
CRF-R, CRF1, CRH-R 1, Corticotropin-releasing factor receptor 1, Corticotropin-releasing hormone receptor 1
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, WB
Citations:
13
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 50 kDa
species reactivity
rat, mouse, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:5000, immunofluorescence: 1:100-1:500, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CRHR1(1394)
General description
Anti-CRHR1 Antibody detects endogenous levels of total CRHR1 protein.
CRHR1 (corticotropin releasing factor receptor 1) is a member of the G-protein-coupled receptor superfamily of brain-gut neuropeptides. It is highly expressed in the amygdala, hippocampus and frontal cortex. It has 13 exons and located on human chromosome 17q12-q22.
Immunogen
The antiserum was produced against synthesized peptide derived from human CRHR1.
Immunogen Range: 75-124
Immunogen Range: 75-124
Application
Anti-CRHR1 antibody has been used in immunoprecipitation and western blotting.
Biochem/physiol Actions
CRHR1 (corticotropin releasing factor receptor 1) blocks the multiplication of endocrine-related cancer cell lines. It helps to initiate signal transduction pathways, that controls various functions like stress, reproduction, immune response and obesity.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
低风险生物材料
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Urocortinergic system in the testes of normal and cryptorchid dogs
Squillacioti C, et al.
Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft, 207, 91-96 (2016)
Association analysis of polymorphisms of the CRHR1 gene with infantile spasms
Yang G, et al.
Molecular Medicine Reports, 12(2), 2539-2546 (2015)
Family Economic Hardship, Corticotropin-Releasing Hormone Receptor Polymorphisms, and Depressive Symptoms in Rural African-American Youths
Chen YF and Brody GH
The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine, 57(2), 235-240 (2015)
Liyang Guo et al.
Cells, 12(1) (2023-01-09)
Chronic sleep disturbances (CSDs) including insomnia, insufficient sleep time, and poor sleep quality are major public health concerns around the world, especially in developed countries. CSDs are major health risk factors linked to multiple neurodegenerative and neuropsychological diseases. It has
Dynamic Alterations of miR-34c Expression in the Hypothalamus of Male Rats after Early Adolescent Traumatic Stress
Li C, et al.
Neural Plast. (2016)
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