SAB4500776
Anti-EPHB1 antibody produced in rabbit
affinity isolated antibody
Synonym(s):
ELK, EPB1, EPHT2, EPTH2, Eph receptor B1
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 109 kDa
species reactivity
human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... EPHB1(2047)
Related Categories
General description
Anti-EPHB1 Antibody detects endogenous levels of total EPHB1 protein.
EPHB1(ephrin type-B receptor 1) belongs to the Eph gene family of receptor tyrosine kinases. It is present in venous endothelial cells during embryonic development to adulthood. It is located on human chromosome 3q22.2.
Immunogen
The antiserum was produced against synthesized peptide derived from human EPHB1/2/3.
Immunogen Range: 631-680
Immunogen Range: 631-680
Biochem/physiol Actions
EPHB1(ephrin type-B receptor 1) participates in carcinogenesis of RCC (renal cell carcinoma). It plays a major role in the growth of nervous and vascular system. It acts as a biomarker for squamous cell/adenosquamous carcinomas and adenocarcinomas of the gallbladder.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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EphB1 and Ephrin-B, new potential biomarkers for squamous cell/adenosquamous carcinomas and adenocarcinomas of the gallbladder
Yuan Y, et al.
Asian Pacific Journal of Cancer Prevention, 15 (2014)
Single nucleotide polymorphism array analysis of uveal melanomas reveals that amplification of CNKSR3 is correlated with improved patient survival
Lake SL, et al.
The American Journal of Pathology (2013)
Loss of expression of EphB1 protein in serous carcinoma of ovary associated with metastasis and poor survival
Wang H, et al.
International Journal of Clinical and Experimental Pathology (2013)
Decreased expression of receptor tyrosine kinase of EphB1 protein in renal cell carcinomas
Zhou S, et al.
International Journal of Clinical and Experimental Pathology, 7 (2014)
Beatriz Garcia-Diaz et al.
Acta neuropathologica, 138(3), 457-476 (2019-04-24)
Schwann cells (SC) enter the central nervous system (CNS) in pathophysiological conditions. However, how SC invade the CNS to remyelinate central axons remains undetermined. We studied SC migratory behavior ex vivo and in vivo after exogenous transplantation in the demyelinated
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