SAB4500895
Anti-ATF5 antibody produced in rabbit
affinity isolated antibody
Synonym(s):
ATF5, Activating transcription factor 5, Cyclic AMP-dependent transcription factor ATF-5, Transcription factor ATFx, cAMP-dependent transcription factor ATF-5
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
6
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 30 kDa
species reactivity
rat, mouse, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ATF5(22809)
General description
Activating transcription factor 5 (ATF5) belongs to the ATF/cAMP response element-binding protein family. It is an anti-apoptotic protein that has 282 amino acids and is located on human chromosome 19q13. It is expressed in various cancers like prostate, rectal, colon, endometrium, breast, ovary, pancreas, gastric etc.
Anti-ATF5 Antibody detects endogenous levels of total ATF5 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human ATF5.
Immunogen Range: 221-270
Immunogen Range: 221-270
Biochem/physiol Actions
Activating transcription factor 5 (ATF5) participates in metabolite homeostasis, cellular proliferation, differentiation, apoptosis and regulation of the cell cycle. It controls neural progenitor cell and adipose-derived stem cell differentiation.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
低风险生物材料
常规特殊物品
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Activating transcription factor 5 enhances radioresistance and malignancy in cancer cells
Ishihara S, et al.
Oncotarget, 6, 4602-4614 (2015)
ATF5 (activating transcription factor 5)
Ching A KK and Wong N
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2011)
Kari A Gaither et al.
PloS one, 15(6), e0225044-e0225044 (2020-07-01)
Cellular stress response mechanisms normally function to enhance survival and allow for cells to return to homeostasis following an adverse event. Cancer cells often co-opt these same mechanisms as a means to evade apoptosis and mitigate a state of constant
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB4500895-100UG | 04061837184444 |