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Merck
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SAB4500988

Anti-PHF3 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

PHD finger protein 3

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IHC
Citations:
3

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 229 kDa

species reactivity

mouse, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:40000, immunohistochemistry: 1:50-1:100

NCBI accession no.

Q92576

UniProt accession no.

Q92576

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... PHF3(23469)

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General description

Anti-PHF3 Antibody detects endogenous levels of total PHF3 protein.
The gene PHF3 (PHD finger protein 3) is mapped to human chromosome 6. It is widely expressed in human tissues.

Immunogen

The antiserum was produced against synthesized peptide derived from human PHF3.

Immunogen Range: 1990-2039

Biochem/physiol Actions

The gene region PTP4A1-PHF3-EYS (protein tyrosine phosphatase type 4A member 1 - PHD finger protein 3 - eyes shut homolog) is associated with alcohol dependence.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
3117658

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Association of rare PTP4A1-PHF3-EYS variants with alcohol dependence.
Lingjun Zuo et al.
Journal of human genetics, 58(3), 178-179 (2013-01-18)
Lingjun Zuo et al.
The American journal on addictions, 23(4), 411-414 (2014-06-26)
We previously reported a risk genomic region (ie, PTP4A1-PHF3-EYS) for alcohol dependence in a genome-wide association study (GWAS). We also reported a rare variant constellation across this region that was significantly associated with alcohol dependence. In the present study, we
Lingjun Zuo et al.
PloS one, 6(11), e26726-e26726 (2011-11-19)
Several genome-wide association studies (GWASs) reported tens of risk genes for alcohol dependence, but most of them have not been replicated or confirmed by functional studies. The present study used a GWAS to search for novel, functional and replicable risk

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