biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 229 kDa
species reactivity
mouse, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:40000, immunohistochemistry: 1:50-1:100
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... PHF3(23469)
General description
Anti-PHF3 Antibody detects endogenous levels of total PHF3 protein.
The gene PHF3 (PHD finger protein 3) is mapped to human chromosome 6. It is widely expressed in human tissues.
The gene PHF3 (PHD finger protein 3) is mapped to human chromosome 6. It is widely expressed in human tissues.
Immunogen
The antiserum was produced against synthesized peptide derived from human PHF3.
Immunogen Range: 1990-2039
Immunogen Range: 1990-2039
Biochem/physiol Actions
The gene region PTP4A1-PHF3-EYS (protein tyrosine phosphatase type 4A member 1 - PHD finger protein 3 - eyes shut homolog) is associated with alcohol dependence.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Lingjun Zuo et al.
PloS one, 6(11), e26726-e26726 (2011-11-19)
Several genome-wide association studies (GWASs) reported tens of risk genes for alcohol dependence, but most of them have not been replicated or confirmed by functional studies. The present study used a GWAS to search for novel, functional and replicable risk
Association of rare PTP4A1-PHF3-EYS variants with alcohol dependence.
Lingjun Zuo et al.
Journal of human genetics, 58(3), 178-179 (2013-01-18)
Lingjun Zuo et al.
The American journal on addictions, 23(4), 411-414 (2014-06-26)
We previously reported a risk genomic region (ie, PTP4A1-PHF3-EYS) for alcohol dependence in a genome-wide association study (GWAS). We also reported a rare variant constellation across this region that was significantly associated with alcohol dependence. In the present study, we
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