SAB4501490
Anti-GPR120 antibody produced in rabbit
affinity isolated antibody
Synonym(s):
G-protein coupled receptor 120, G-protein coupled receptor 129, G-protein coupled receptor GT01, G-protein coupled receptor PGR4, GPR120
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, WB
Citations:
5
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 42 kDa
species reactivity
human, mouse, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, immunofluorescence: 1:100-1:500, western blot: 1:500-1:1000
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GPR120(338557)
General description
Anti-GPR120 Antibody detects endogenous levels of total GPR120 protein.
GPR120 (G-protein coupled receptor 120) is also called as free fatty acid receptor 4 (FFA4). It is present in mature bone cells. It is located on human chromosome 12q24.
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR120.
Immunogen Range: 221-270
Immunogen Range: 221-270
Application
Anti-GPR120 antibody has been used in immunohistochemistry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Immunohistochemistry (1 paper)
Biochem/physiol Actions
GPR120 (G-protein coupled receptor 120) promotes bone formation and suppresses bone resorption, thereby it plays an important role in bone metabolism.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
低风险生物材料
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Chromosome 12q24.31-q24.33 deletion causes multiple dysmorphic features and developmental delay: First mosaic patient and overview of the phenotype related to 12q24qter defects.
Al-Zahrani J, et al.
Molecular Cytogenetics, 4, 9-9 (2011)
Patricia Widmayer et al.
Frontiers in physiology, 6, 53-53 (2015-03-17)
Long-term intake of dietary fat is supposed to be associated with adaptive reactions of the organism and it is assumptive that this is particularly true for fat responsive epithelial cells in the mucosa of the gastrointestinal tract. Recent studies suggest
Yufeng Zhao et al.
Molecular medicine reports, 17(2), 3281-3287 (2017-12-20)
Grifolic acid is a phenolic compound that was first extracted from the mushroom Albatrellus confluens; it acts as an agonist of the free fatty acid receptor (FFAR4). FFAR4 is expressed in macrophages and mediates the anti‑inflammatory effects of n‑3 unsaturated free
Free Fatty Acid Receptor 4 (GPR120) Stimulates Bone Formation and Suppresses Bone Resorption in the Presence of Elevated n-3 Fatty Acid Levels.
Ahn SH, et al.
Endocrinology, 157(7), 2621-2635 (2016)
Seong Hee Ahn et al.
Endocrinology, 157(7), 2621-2635 (2016-05-05)
Free fatty acid receptor 4 (FFA4) has been reported to be a receptor for n-3 fatty acids (FAs). Although n-3 FAs are beneficial for bone health, a role of FFA4 in bone metabolism has been rarely investigated. We noted that
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