SAB4501903
Anti-MMP-15 antibody produced in rabbit
affinity isolated antibody
Synonym(s):
MATRIX METALLOPROTEINASE 15, MEMBRANE-TYPE, MEMBRANE-TYPE MATRIX METALLOPROTEINASE 2, MT2-MMP, matrix metalloproteinase 15 (membrane-inserted)
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
5
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 75 kDa
species reactivity
human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MMP15(4324)
General description
Matrix metallopeptidase 15 (MMP-15) is encoded by the gene mapped to human chromosome l Iq22.2-22.3. The encoded protein belongs to the membrane-type matrix metalloproteinases (MT-MMPs).
Anti-MMP-15 Antibody detects endogenous levels of total MMP-15 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human MMP-15.
Immunogen Range: 611-660
Immunogen Range: 611-660
Biochem/physiol Actions
Matrix metallopeptidase 15 (MMP-15) is implicated in the activation of pro-MMP-2 and pro-MMP-13. It is also facilitates tumor necrosis factor a processing. MMP-15 might promote various types of cancer progression, including non-small cell lung cancer (NSCLC). In addition, it also promotes gastric cancer (GC) invasion and metastasis. Thus, this protein can be used as a potent prognostic marker for GC patients.
Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Find documentation for the products that you have recently purchased in the Document Library.
MT2-MMP expression associates with tumor progression and angiogenesis in human lung cancer
Chen L, et al.
International Journal of Clinical and Experimental Pathology, 7(6), 3469-3469 (2014)
The role of MT2-MMP in cancer progression
Ito E, et al.
Biochemical and Biophysical Research Communications, 393(2), 222-227 (2010)
Increased MT2-MMP expression in gastric cancer patients is associated with poor prognosis
Xu X, et al.
International Journal of Clinical and Experimental Pathology, 8(2), 1985-1985 (2015)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB4501903-100UG | 04061837188664 |