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Merck
CN

SAB4502469

Anti-GPR126 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

GPR126, Probable G-protein coupled receptor 126

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF
Citations:
5
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 136 kDa

species reactivity

human, mouse

concentration

~1 mg/mL

technique(s)

ELISA: 1:20000, immunofluorescence: 1:100-1:500

NCBI accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GPR126(57211)

General description

G protein-coupled receptor 126 (GPR126) belongs to the adhesion-G protein-coupled receptor (GPCR) family. It is an endothelial cell-enriched gene. The gene is located on human chromosome 6q24.2.
The GPR126 (adhesion G protein-coupled receptor G6) gene codes for a protein that contains an extracellular domain, a seven transmembrane domain at the N-terminal and an intracellular domain in its C-terminal.

Immunogen

The antiserum was produced against synthesized peptide derived from human GPR126.

Immunogen Range: 1091-1140

Biochem/physiol Actions

GPR126 (adhesion G protein-coupled receptor G6) controls the homeostasis of periodontal ligament tissue. GPR126 is responsible for axon myelination of peripheral neurons in human, mice and fish. This gene mediates endothelial cell proliferation and migration, and tube formation, thereby contributing to angiogenesis, which is necessary for overall growth, wound healing and tumor progression.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable



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