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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Product Name
Anti-SNAP25 antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 23 kDa
species reactivity
mouse, human, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SNAP25(6616)
Biochem/physiol Actions
SNAP25 (synaptosome associated protein 25) protein is involved in extracellular trafficking and mediates the process of exocytosis and endocytosis by promoting fusion of vesicles with the plasma membrane. SNAP25 is needed for rapid excitatory and inhibitory neurotransmission of neurons producing glutamate and GABA (gamma aminobutyric acid).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Anti-SNAP25 antibody detects endogenous levels of total SNAP25 protein.
The SNAP25 (synaptosome associated protein 25) gene is mapped to human chromosome 20p12.2. The encoded protein belongs to the family of SNARE (small ILF3/NF90-associated RNA E) complex.
Immunogen
The antiserum was produced against synthesized peptide derived from human SNAP25.
Immunogen Range: 151-200
Immunogen Range: 151-200
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25.
Rasnitsyn A
PLoS ONE, 12(6), 1-24 (2017)
Biased paternal transmission of SNAP-25 risk alleles in attention-deficit hyperactivity disorder.
Kustanovich V
Molecular Psychiatry, 8(3), 309-315 (2003)
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