SAB4502826
Anti-SNAP25 antibody produced in rabbit
affinity isolated antibody
Synonym(s):
SN25, SNAP, SNP25, SUP, Super protein
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 23 kDa
species reactivity
mouse, human, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SNAP25(6616)
General description
Anti-SNAP25 antibody detects endogenous levels of total SNAP25 protein.
The SNAP25 (synaptosome associated protein 25) gene is mapped to human chromosome 20p12.2. The encoded protein belongs to the family of SNARE (small ILF3/NF90-associated RNA E) complex.
Immunogen
The antiserum was produced against synthesized peptide derived from human SNAP25.
Immunogen Range: 151-200
Immunogen Range: 151-200
Biochem/physiol Actions
SNAP25 (synaptosome associated protein 25) protein is involved in extracellular trafficking and mediates the process of exocytosis and endocytosis by promoting fusion of vesicles with the plasma membrane. SNAP25 is needed for rapid excitatory and inhibitory neurotransmission of neurons producing glutamate and GABA (gamma aminobutyric acid).
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25.
Rasnitsyn A
PLoS ONE, 12(6), 1-24 (2017)
Biased paternal transmission of SNAP-25 risk alleles in attention-deficit hyperactivity disorder.
Kustanovich V
Molecular Psychiatry, 8(3), 309-315 (2003)
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