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Merck
CN

SAB4503125

Anti-ZNF148, N-Terminal antibody produced in rabbit

affinity isolated antibody

Synonym(s):

β enolase repressor factor 1, G-rich box-binding protein, Transcription factor BFCOL1, Transcription factor ZBP-89, ZBP89

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD02264224

Key Documents

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Product Name

Anti-ZNF148, N-Terminal antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 88 kDa

species reactivity

mouse, rat, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

Q9UQR1

UniProt accession no.

Q9UQR1

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... ZNF148(7707)

Biochem/physiol Actions

Znf148 (zinc finger protein 148) is known to regulate cell growth and apoptosis. ZNF148 is involved in tumor growth, invasion and metastasis. Znf148 possesses tumor suppressor activity. Upregulation of the ZNF148 gene is observed in colorectal cancer and Znf148 brings about apoptosis, induced by p53-dependent or in an independent manner in cancer cells.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Anti-ZNF148 Antibody detects endogenous levels of total ZNF148 protein.
The ZNF148 (zinc finger protein 148) gene is mapped to human chromosome 3q21.2. The encoded protein contains four C2H2 zinc finger motifs.

Immunogen

The antiserum was produced against synthesized peptide derived from human ZNF148.

Immunogen Range: 61-110

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
3111914

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Truncating de novo mutations in the Kruppel-type zinc-finger gene ZNF148 in patients with corpus callosum defects, developmental delay, short stature, and dysmorphisms
Stevens SJ, et al.
Genome Medicine, 8(1), 131-131 (2016)
Expression of ZNF148 in different developing stages of colorectal cancer and its prognostic value: a large Chinese study based on tissue microarray.
Gao XH, et al.
Cancer, 119(12), 2212-2222 (2013)
Interaction between ZBP-89 and p53 mutants and its contribution to effects of HDACi on hepatocellular carcinoma
Zhang CZ, et al.
Cell Cycle, 11(2), 322-334 (2012)
High-expression of ZBP-89 correlates with distal metastasis and poor prognosis of patients in clear cell renal cell carcinoma.
Cai MY, et al.
Biochemical and Biophysical Research Communications, 426(4), 636-642 (2012)
Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease
Bomprezzi R, et al.
Human Molecular Genetics, 12(17), 2191-2199 (2003)

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