SAB4503125
Anti-ZNF148, N-Terminal antibody produced in rabbit
affinity isolated antibody
别名:
β enolase repressor factor 1, G-rich box-binding protein, Transcription factor BFCOL1, Transcription factor ZBP-89, ZBP89
产品名称
Anti-ZNF148, N-Terminal antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 88 kDa
species reactivity
mouse, rat, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ZNF148(7707)
Biochem/physiol Actions
Znf148 (zinc finger protein 148) is known to regulate cell growth and apoptosis. ZNF148 is involved in tumor growth, invasion and metastasis. Znf148 possesses tumor suppressor activity. Upregulation of the ZNF148 gene is observed in colorectal cancer and Znf148 brings about apoptosis, induced by p53-dependent or in an independent manner in cancer cells.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Anti-ZNF148 Antibody detects endogenous levels of total ZNF148 protein.
The ZNF148 (zinc finger protein 148) gene is mapped to human chromosome 3q21.2. The encoded protein contains four C2H2 zinc finger motifs.
Immunogen
The antiserum was produced against synthesized peptide derived from human ZNF148.
Immunogen Range: 61-110
Immunogen Range: 61-110
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Truncating de novo mutations in the Kruppel-type zinc-finger gene ZNF148 in patients with corpus callosum defects, developmental delay, short stature, and dysmorphisms
Stevens SJ, et al.
Genome Medicine, 8(1), 131-131 (2016)
Expression of ZNF148 in different developing stages of colorectal cancer and its prognostic value: a large Chinese study based on tissue microarray.
Gao XH, et al.
Cancer, 119(12), 2212-2222 (2013)
Interaction between ZBP-89 and p53 mutants and its contribution to effects of HDACi on hepatocellular carcinoma
Zhang CZ, et al.
Cell Cycle, 11(2), 322-334 (2012)
High-expression of ZBP-89 correlates with distal metastasis and poor prognosis of patients in clear cell renal cell carcinoma.
Cai MY, et al.
Biochemical and Biophysical Research Communications, 426(4), 636-642 (2012)
Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease
Bomprezzi R, et al.
Human Molecular Genetics, 12(17), 2191-2199 (2003)
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