SAB4504642
Anti-phospho-RIPK2 (pSer176) antibody produced in rabbit
affinity isolated antibody
Synonym(s):
Anti-CARD3, Anti-CARDIAK, Anti-CCK, Anti-GIG30, Anti-RICK, Anti-RIP2
Sign In to View Organizational & Contract Pricing
Select a Size
About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 61 kDa
species reactivity
mouse, rat, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer176)
Gene Information
human ... RIPK2(8767)
Related Categories
General description
Receptor interacting protein kinase 2 (RIP2K) has an N-terminal dual-specificity ser/tyr kinase domain. This gene is a member of the TKL kinase family (tyrosine kinase-like). RIP2K is located on human chromosome 8q21.
Immunogen
The antiserum was produced against synthesized peptide derived from human RIPK2 around the phosphorylation site of Ser176.
Immunogen Range: 146-195
Immunogen Range: 146-195
Biochem/physiol Actions
Receptor interacting protein kinase 2 (RIP2K) can act as a new target for anti-inflammatory drugs. This gene participates in multiple nuclear factor-κB (NFκB) activation pathways and human colon tumorigenesis.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation
Pellegrini E, et al.
PLoS ONE, 12(5) (2017)
Genetics of inflammasome-associated disorders: a lesson in the guiding principals of inflammasome function
Rodrigue-Gervais IG and Saleh M
European Journal of Immunology, 40(3), 643-648 (2010)
Receptor-interacting protein 2 (RIP2) gene polymorphisms are associated with increased risk of subclinical atherosclerosis and clinical and metabolic parameters. The Genetics of Atherosclerotic Disease (GEA) Mexican study
Posadas-Sanchez R, et al.
Experimental and Molecular Pathology, 102(1), 1-6 (2017)
Huisheng Liu et al.
Journal of virology, 93(11) (2019-03-22)
The role of nucleotide-binding oligomerization domain 2 (NOD2) in foot-and-mouth disease virus (FMDV)-infected cells remains unknown. Here, we showed that FMDV infection activated NOD2-mediated beta interferon (IFN-β) and nuclear factor-κB (NF-ĸB) signaling pathways. NOD2 inhibited FMDV replication in the infected
Ravi Bharadwaj et al.
Immunity, 56(5), 998-1012 (2023-04-29)
Cytosolic innate immune sensing is critical for protecting barrier tissues. NOD1 and NOD2 are cytosolic sensors of small peptidoglycan fragments (muropeptides) derived from the bacterial cell wall. These muropeptides enter cells, especially epithelial cells, through unclear mechanisms. We previously implicated
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service