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Merck
CN

SAB4700022

Monoclonal Anti-CD147 antibody produced in mouse

clone MEM-M6/1, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-BSG, Anti-Basigin, Anti-Neurothelin

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
MEM-M6/1, monoclonal
Application:
flow cytometry
Species reactivity:
human
Citations:
1
Technique(s):
flow cytometry: suitable
Uniprot accession no.:
P35613

Key Documents

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Product Name

Monoclonal Anti-CD147 antibody produced in mouse, clone MEM-M6/1, purified immunoglobulin, buffered aqueous solution

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

MEM-M6/1, monoclonal

form

buffered aqueous solution

species reactivity

human

concentration

1 mg/mL

technique(s)

flow cytometry: suitable

isotype

IgG1

NCBI accession no.

NM_001728.2

UniProt accession no.

P35613

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... BSG(682)

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Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

The antibody MEM-M6/1 recognizes an epitope in the N-terminal Ig domain (D1) of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes.

Immunogen

Protein A-CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2-and CH3 domain of human IgG1 (CD147Rg is secreted by transfectants as a dimer)

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 10 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
528430
522909
513223
515147
E98K

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Gina Pistol et al.
Journal of cellular and molecular medicine, 11(2), 339-348 (2007-05-10)
The cellular and molecular mechanisms involved in many abnormalities described in Systemic Lupus Erythematosus (SLE) are still unclear. Some of these abnormalities referred to the hyperactivation of T lymphocytes and the enhanced secretion of MMP-9 by peripheral blood mononuclear cells

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