SAB4700394
Anti-Integrin beta 1 (CD29) Antibody
mouse monoclonal, MEM-101A
Synonym(s):
Anti-ITGB1, Anti-Integrin β1 chain
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Product Name
Monoclonal Anti-CD29 antibody produced in mouse, clone MEM-101A, purified immunoglobulin, buffered aqueous solution
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
MEM-101A, monoclonal
form
buffered aqueous solution
species reactivity
human, pig, canine
concentration
1 mg/mL
technique(s)
flow cytometry: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ITGB1(3688)
Related Categories
Physical form
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
Immunogen
Raji Burkitt′s lymphoma cell line
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Flow cytometry/Cell sorting (1 paper)
Flow cytometry/Cell sorting (1 paper)
Biochem/physiol Actions
Cluster of differentiation 29 (CD29) acts as an adhesive molecule in the development of de novo focal contact, keratinocyte migration and re-epithelialization of wound tissue. CD29 with/without CD27 induce apoptosis, in association with a multifunctional protein galectin (Gal)-3.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Cluster of differentiation 29 (CD29), also known as integrin subunit β 1 (ITGB1), is a mechanosensor, encoded by the gene mapped to human chromosome 10p11.22. It is present in both normal cells and tumor-associated cells. The encoded protein has ubiquitous expression with a molecular mass of 130kDa.
The antibody MEM-101A reacts with CD29 (integrin beta1 chain), a 130 kDa single chain type I glycoprotein expressed as a heterodimer (non-covalently associated with the integrin alpha subunits 1-6). CD29 is broadly expressed on majority of hematopoietic and non-hematopoietic cells (leukocytes, platelets, fibroblasts, endothelial cells, epithelial cells and mast cells).
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Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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CD29 and CD7 Mediate Galectin-3-Induced Type II T-Cell Apoptosis
Fukumori T
Cancer Research, 63, 8302-8311 (2003)
β1 integrin signaling in asymmetric migration of keratinocytes under mechanical stretch in a co-cultured wound repair model
Lu D
BioMedical Engineering OnLine, 15 (2016)
β1 Integrin as a Prognostic and Predictive Marker in Triple-Negative Breast Cancer
Yin HL
International Journal of Molecular Sciences, 17 (2016)
Genomic Aberrations Associated with Erlotinib Resistance in Non-small Cell Lung Cancer Cells
Serizawa M
Anticancer Research, 33, 5223-5233 (2013)
Qifei Wang et al.
Molecular medicine reports, 13(6), 4636-4642 (2016-04-16)
The aim of the present study was to evaluate the different expression levels of thyroid hormone responsive (THRSP; Spot14)/S14 related, Mig12 (S14R) during bone marrow mesenchymal stem cell (BM-MSC) adipogenesis in adolescent idiopathic scoliosis (AIS) patients. MSCs were retrospectively isolated from
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