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Merck
CN

SAB4702012

Monoclonal Anti-CD307b purified produced in mouse

Synonym(s):

FcRH2, FcRL2, IFGP4, IRTA4, SPAP1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
B24, monoclonal
Application:
FACS
Citations:
-
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conjugate

unconjugated

Quality Segment

antibody product type

primary antibodies

clone

B24, monoclonal

form

buffered aqueous solution

species reactivity

human

concentration

1 mg/ml

technique(s)

flow cytometry: suitable

isotype

IgG1κ

UniProt accession no.

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... FCRL2(79368)

General description

CD307b is a type I transmembrane glycoprotein of the Fc receptor family. It contains one ITAM motif and two ITIM motifs in its cytoplasmic domain. It is expressed in spleen and lymph nodes in mature B cells and memory B cells. CD307b may be a prognostic marker for chronic lymphocytic leukemia.

Immunogen

DNA-immunization followed by a boost with CD307b transfected cells

Biochem/physiol Actions

The mouse monoclonal antibody B24 recognizes an extracellular epitope of CD307b, a transmembrane glycoprotein expressed mainly in mature and memory B cells.

Physical form

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preparation Note

Purified by protein-A affinity chromatography.
Store at 2-8°C. Do not freeze.

Other Notes

The antibody solution should be gently mixed before use.


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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