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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
C33, monoclonal
Application:
FACS, FUNC, ICC, IHC, IP, WB
Citations:
-
conjugate
unconjugated
antibody product type
primary antibodies
clone
C33, monoclonal
form
buffered aqueous solution
species reactivity
human
concentration
1 mg/ml
technique(s)
FUNC: suitable, flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG2a
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
human ... CD82(3732)
General description
CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.
Immunogen
C91/PL (human HTLV-1+ T cell line)
Biochem/physiol Actions
The mouse monoclonal antibody C33 recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
Physical form
Phosphate buffered saline (PBS), pH 7.4
Preparation Note
Purified by protein-A affinity chromatography.
Store at 2-8°C. Do not freeze.
Other Notes
The antibody solution should be gently mixed before use.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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