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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
UP-H2, monoclonal
Application:
FACS, FUNC, IP, WB
Citations:
-
conjugate
unconjugated
antibody product type
primary antibodies
clone
UP-H2, monoclonal
form
buffered aqueous solution
species reactivity
human
concentration
1 mg/ml
technique(s)
FUNC: suitable, flow cytometry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG1κ
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
human ... CD300E(342510)
General description
CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.
Immunogen
CD300e-HA-transfected cells
Biochem/physiol Actions
The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
Physical form
Phosphate buffered saline (PBS), pH 7.4
Preparation Note
Purified by protein-A affinity chromatography.
Store at 2-8°C. Do not freeze.
Other Notes
The antibody solution should be gently mixed before use.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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