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Merck
CN

SAB5200006

Monoclonal Anti-CRYAA antibody produced in mouse

clone 1H3.B8, 1 mg/mL, purified immunoglobulin

Synonym(s):

Anti-Acry1, Anti-Alpha A Crystallin, Anti-CRYA1, Anti-CRYAA, Anti-Heat Shock protein beta4, Anti-HspB4

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1H3.B8, monoclonal

form

buffered aqueous glycerol solution

mol wt

antigen predicted mol wt 20 kDa

species reactivity

bovine, rat, mouse, human

concentration

1 mg/mL

technique(s)

indirect ELISA: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NP_000385.1

UniProt accession no.

P02489

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CRYAA(1409)

Immunogen

Native Alpha Crystallin

Biochem/physiol Actions

Detects α-crystallin at ~20 kDa. Does not cross-react with αB-crystallin, βL-crystallin, βH- crystallin, γ-crystallin, Hsp25, Hsp27 or Hsp47 proteins.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in PBS, pH 7.2, in 50% glycerol, and 0.09% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0811

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Shiwani Sharma et al.
Molecular vision, 24, 801-817 (2019-02-05)
Pseudoexfoliation (PEX) syndrome is an age-related progressive disease of the extracellular matrix with ocular manifestations. PEX is clinically diagnosed by the presence of extracellular exfoliative deposits on the anterior surface of the ocular lens. PEX syndrome is a major risk
Andrea Schlotterer et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(3), 4141-4153 (2018-11-30)
The aim of this study was to evaluate whether damage to the neurovascular unit in diabetes depends on reactive metabolites such as methylglyoxal (MG), and to assess its impact on retinal gene expression. Male Wistar rats were supplied with MG

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