SAB5200898
Monoclonal Anti-Glun2A/Nr2A - Apc antibody produced in mouse
clone S327-95, purified immunoglobulin
Synonym(s):
Anti-GRIN2A, Anti-HNR2A, Anti-NMDA 2A
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
Allophycocyanin conjugate
Clone:
S327-95, monoclonal
Application:
ICC, IHC, WB
Citations:
5
biological source
mouse
Quality Segment
conjugate
Allophycocyanin conjugate
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
S327-95, monoclonal
form
buffered aqueous solution
mol wt
antigen predicted mol wt 170 kDa
species reactivity
human, rat, mouse
concentration
1 mg/mL
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable
isotype
IgG2a
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Grin2a(24409)
General description
The GRIN2A (glutamate ionotropic receptor NMDA (N-methyl-D -aspartate) type subunit 2A) gene is mapped to human chromosome 16p13.2. It codes for a transmembrane ligand-gated ion channel called N-methyl-D-aspartate glutamate receptor α2 subunit.
Immunogen
Fusion protein amino acids 75-325 (extracellular N-terminus) of rat GluN2A/NR2A
Biochem/physiol Actions
The GRIN2A (glutamate ionotropic receptor NMDA (N-methyl-D-aspartate) type subunit 2A) gene is associated with focal epilepsy and impaired speech. NMDA glutamate receptor α2 subunit is involved in neuron development, maintains synaptic plasticity and is associated with memory. GRIN2A is related to schizophrenia and Alzheimer′s disease. Mutations in GRIN2A gene upregulates NMDA action and might lead to melanoma tumors. NMDA participates in apoptosis and proliferation of cancer cells.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
PBS pH7.4, 50% glycerol, 0.09% sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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