SAB5500102
Anti-EZH2 antibody, Rabbit monoclonal
recombinant, expressed in proprietary host, clone SP129, affinity isolated antibody
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
Quality Level
recombinant
expressed in proprietary host
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
SP129, monoclonal
species reactivity
human (tested)
species reactivity (predicted by homology)
monkey, frog, mouse, rat
technique(s)
flow cytometry: 1:100
immunoblotting: 1:25
immunohistochemistry: 1:100
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... EZH2(2146)
Related Categories
General description
KMT6/Enhancer of zeste homologue 2 (EZH2) is a histone lysine methyl transferase associated with transcriptional repression. It is a component of the polycomb repressive complexes PRC2 and PRC3. The PRC2 complex catalyses histone H3 K27 trimethylation. EZH2 is ubiquitously expressed during early embryo genesis, and becomes restricted to the central and peripheral nervous systems and sites of fetal hematopoiesis during later development. EZH2 is highly expressed in follicular T-cells and in a variety of tumors such as lymphoma, breast and prostate.
Immunogen
Synthetic peptide corresponding to C-terminus of human EZH2 protein.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Ivan Osokine et al.
Cell reports, 38(5), 110329-110329 (2022-02-03)
A little-appreciated feature of early pregnancy is that embryo implantation and placental outgrowth do not evoke wound-healing responses in the decidua, the specialized endometrial tissue that surrounds the conceptus. Here, we provide evidence that this phenomenon is partly due to
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