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Merck
CN

SAB5500139

Anti-MAGE-A1 antibody, Rabbit monoclonal

recombinant, expressed in proprietary host, clone SP188, affinity isolated antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Product Name

Anti-MAGE-A1 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP188, affinity isolated antibody

biological source

rabbit

recombinant

expressed in proprietary host

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

SP188, monoclonal

species reactivity

human (tested)

technique(s)

flow cytometry: 1:400
immunoblotting: 1:400
immunohistochemistry: 1:100

isotype

IgG

UniProt accession no.

P43355

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... MAGEA1(4100)

Related Categories

Biochem/physiol Actions

Members of MAGE family play a vital role in maintaining normal cellular physiology. Melanoma-associated antigen 1 (MAGE-A1) serves as a target antigen of patient-derived CD8+ T cells in melanoma. It might be potential target for treating melanoma patients.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Melanoma-associated antigen 1 (MAGE-A1) is one of the melanoma associated antigens (MAAs). MAGE-A1 is highly expressed in testis and some human solid tumors such as melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian and renal cell carcinomas.

Immunogen

Synthetic peptide derived from the C-terminus of human MAGE-A1 protein.

Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
170726B
170726A
150515H
150515G
150515F

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MAGE-F1, a novel ubiquitously expressed member of the MAGE superfamily.
Stone B, et al.
Gene, 267(2), 173-182 (2001)
MAGE-A1 promotes melanoma proliferation and migration through C-JUN activation.
Wang D, et al.
Biochemical and Biophysical Research Communications, 473(4), 959-965 (2016)

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