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Merck
CN

SAB5700369

Anti-Phospho-PDGFR beta-Y751 antibody produced in rabbit

Synonym(s):

CD140B, IBGC4, IMF1, JTK12, KOGS, PDGF Receptor beta, PDGFR, PDGFR beta, PDGFR-1, PDGFR1, PDGFRB, PENTT

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

123
 37

species reactivity

human, mouse

concentration

1.73 mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

P09619

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr751)

Quality Level

100

Gene Information

human ... PDGFRB(5159)

General description

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Immunogen

A synthetic phosphorylated peptide around Y751 of human PDGFR beta (NP_002600.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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