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Safety Information

SAB5700380

Sigma-Aldrich

Anti-Phospho-GSK3B-Y216 + GSK3A-Y279 antibody produced in rabbit

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Synonym(s):
GSK3B, gsk-3β

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

46
 48

species reactivity

human

concentration

3.08 mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

P49841

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr216/pTyr279)

Gene Information

human ... GSK3B(2932)

General description

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic phosphorylated peptide around Y216 of human GSK3B (NP_001139628).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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