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Merck
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SAB5700454

Anti-Phospho-FLNA-S2152 antibody produced in rabbit

Synonym(s):

ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FLNA, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD, filamin-A

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

280

species reactivity

rat, mouse, human

concentration

1.7 mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

P21333

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer2152)

Quality Level

100

Gene Information

human ... FLNA(2316)

General description

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic phosphorylated peptide around S2152 of human FLNA (NP_001104026.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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