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Merck
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SAB5700485

Anti-Phospho-DPYSL2-T514 antibody produced in rabbit

Synonym(s):

CRMP-2, CRMP2, DHPRP2, DPYSL2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
rat, human, mouse
Application:
western blot
Technique(s):
western blot: 1:500-1:2000
Citations:
Uniprot accession no.:
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biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

58
62

species reactivity

rat, human, mouse

concentration

2.63 mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pThr514)

Quality Level

Gene Information

human ... DPYSL2(1808)

General description

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer′s disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding T514 of human DPYSL2

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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