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CN

SAB5700571

Anti-Phospho-PDGFRB-Y771 antibody produced in rabbit

Synonym(s):

CD140B, IBGC4, IMF1, JTK12, KOGS, PDGF Receptor beta, PDGFR, PDGFR beta, PDGFR-1, PDGFR1, PDGFRB, PENTT

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
rat, human, mouse
Application:
WB
Citations:
-

Key Documents

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Quality Level

100

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

124

species reactivity

rat, human, mouse

concentration

0.49mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

P09619

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr771)

Gene Information

human ... PDGFRB(5159)

General description

The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia.

Immunogen

A phospho synthetic peptide corresponding to residues surrounding Y771 of human PDGFRB.

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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