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Merck
CN

SAB5700609

Anti-FasLG antibody produced in rabbit

Synonym(s):

ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, FASLG, Fas ligand, FasL, FasLG, TNFSF6, TNLG1A

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

14
 31

species reactivity

human, mouse, rat

concentration

1.52 mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

P48023

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... FasLG(356)

General description

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FasLG (NP_000630.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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