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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Technique(s):
immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000
Uniprot accession no.:
Application:
IHC, WB
Citations:
-
biological source
rabbit
Quality Level
antibody product type
primary antibodies
clone
monoclonal
form
liquid
species reactivity
rat, human, mouse
concentration
0.85 mg/mL
technique(s)
immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... BBC3(27113)
General description
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Immunogen
A synthesized peptide derived from human PUMA
Physical form
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
低风险生物材料
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB5701486-100UL | 04065267670607 |