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Merck
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SAB5701512

Anti-tPA/PLAT antibody produced in rabbit

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About This Item

NACRES:
NA.43
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
monoclonal
Application:
IHC, WB
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody product type

primary antibodies

clone

monoclonal

form

liquid

species reactivity

human, rat, mouse

concentration

1.3 mg/mL

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PLAT(5327)

General description

This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Immunogen

A synthesized peptide derived from human tPA/tPA/PLAT

Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品

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Global Trade Item Number

SKUGTIN
SAB5701512-100UL04065267670867