SAB5701694
Anti-Cortactin antibody produced in rabbit
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About This Item
NACRES:
NA.43
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
monoclonal
Application:
IHC, WB
Citations:
-
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody product type
primary antibodies
clone
monoclonal
form
liquid
species reactivity
mouse, rat, human
concentration
0.21 mg/mL
technique(s)
immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CTTN(2017)
General description
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010]
Immunogen
A synthesized peptide derived from human Cortactin
Physical form
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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