SAB5701766
Anti-Phospho-RB-S780 antibody produced in rabbit
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
NACRES:
NA.43
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human
Application:
IHC, WB
Citations:
-
biological source
rabbit
Quality Segment
antibody product type
primary antibodies
clone
polyclonal
form
liquid
species reactivity
human
concentration
0.49 mg/mL
technique(s)
immunohistochemistry: 1:50-1:100, immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer780)
Gene Information
human ... RB1(5925)
General description
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Immunogen
A phospho specific peptide corresponding to residues surrounding S780 of human RB
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Still not finding the right product?
Try our Product Selector Tool to narrow your options
Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.