SAB5701916
Anti-Phospho-Cdc6-S54 antibody produced in rabbit
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About This Item
NACRES:
NA.43
UNSPSC Code:
12352203
Clone:
monoclonal
Species reactivity:
mouse, human
Application:
WB
Citations:
-
biological source
rabbit
Quality Segment
antibody product type
primary antibodies
clone
monoclonal
form
liquid
species reactivity
mouse, human
concentration
0.33 mg/mL
technique(s)
western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer52)
Gene Information
human ... CDC6(990)
General description
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]
Immunogen
A phospho specific peptide corresponding to residues surrounding S54 of human Cdc6
Physical form
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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