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Merck
CN

SAB5701984

Anti-UBE4B Antibody, clone 1D7K5, Rabbit Monoclonal

Synonym(s):

E4, HDNB1, UBOX3, UFD2, UFD2A

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
rat, human
Conjugate:
unconjugated
Application:
WB
Citations:
-
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biological source

rabbit

Quality Segment

conjugate

unconjugated

material

colorless

clone

1D7K5, monoclonal

form

liquid

mol wt

146 kDa

species reactivity

rat, human

concentration

0.50 mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSL

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... UBE4B(10277)

General description

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE4B (O95155).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB


Storage Class

10 - Combustible liquids

wgk

WGK 1



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