SAB5701992
Anti-BRMS1 Antibody, clone 5Y8J3, Rabbit Monoclonal
Synonym(s):
BRMS1, breast cancer metastasis-suppressor 1
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.46
biological source
rabbit
Quality Level
conjugate
unconjugated
material
colorless
clone
5Y8J3, monoclonal
form
liquid
species reactivity
rat, human, rat
concentration
1.20 mg/mL
technique(s)
immunohistochemistry: 1:50 - 1:200
color
colorless
isotype
IgG
immunogen sequence
MPVQPPSKDTEEMEAEGDSAAEMNGEEEESEEERSGSQTESEEESSEMDDEDYERRRSECVSEMLDLEKQFSELKEKLFRERLSQLRLRLEEVGAERAPE
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... BRMS1(25855)
General description
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BRMS1 (Q9HCU9).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
IHC
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Regulatory Information
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