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Merck
CN

SAB5701993

Anti-HBG1 Antibody, clone 6F1A8, Rabbit Monoclonal

Synonym(s):

HBG-T2, HBGA, HBGR, HSGGL1, PRO2979

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

material

colorless

clone

6F1A8, monoclonal

form

liquid

mol wt

12 kDa

species reactivity

mouse, mouse

concentration

0.40 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVD

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... HBG1(3047)

Application

WB, IHC, IF/ICC

General description

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HBG1 (P69891).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

常规特殊物品
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