SAB5702097
Anti-Insulin Antibody, clone 4C3Y9, Rabbit Monoclonal
Synonym(s):
IDDM,IDDM1,IDDM2,ILPR,IRDN,MODY10,INS,Insulin,insulin
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.46
biological source
rabbit
Quality Level
conjugate
unconjugated
material
colorless
clone
4C3Y9, monoclonal
form
liquid
mol wt
12 kDa
species reactivity
mouse, rat
concentration
0.8 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSIC
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... INS(3630)
General description
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Insulin (P01308).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IHC, IF/ICC
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Regulatory Information
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