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UNSPSC Code:
12352203
NACRES:
NA.46
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Product Name

Anti-Neurofilament H Antibody, clone 7L2V7, Rabbit Monoclonal,

biological source

rabbit

Quality Level

100

material

colorless

clone

7L2V7, monoclonal

form

liquid

species reactivity

rat, human, rat

concentration

1.41 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200
immunoprecipitation (IP): 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

AKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE

UniProt accession no.

P12036

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NEFH(4744)

General description

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 550-650 of human Neurofilament H (P12036).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC, IF/ICC, IP

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

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