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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
10F7U6, monoclonal
form
liquid
mol wt
70 kDa
species reactivity
rat, rat, human
concentration
0.50 mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMKAETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQI
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... RACGAP1(29127)
Application
WB
General description
This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RGAP1 (Q9H0H5).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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