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Merck
CN

SAB5702194

Anti-NF-κB2 Antibody, clone 4K3V3, Rabbit Monoclonal

Synonym(s):

CVID10,H2TF1,LYT-10,LYT10,NF-kB2,p100,p49/p100,p52

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
4K3V3, monoclonal
Application:
IHC, WB
Species reactivity:
rat, rat, human
Citations:
Technique(s):
immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000
Uniprot accession no.:
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biological source

rabbit

conjugate

unconjugated

material

colorless

clone

4K3V3, monoclonal

form

liquid

mol wt

120 kDa

species reactivity

rat, rat, human

concentration

0.25 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

LLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGLEEGVRLLRGPETRDKLPSTAEVKEDSAYGSQSVEQEA

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... NFKB2(4791)

Application

WB, IHC

General description

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Immunogen

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 745-877 of human NF-κB2 (Q00653).

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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