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Key Documents

SAB5702208

Sigma-Aldrich

Anti-DBF4 Antibody, clone 0S8I5, Rabbit Monoclonal

Synonym(s):

ASK, CHIF, DBF4A, ZDBF1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

100

conjugate

unconjugated

material

colorless

clone

0S8I5, monoclonal

form

liquid

mol wt

77 kDa

species reactivity

human

concentration

0.35 mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

MNSGAMRIHSKGHFQGGIQVKNEKNRPSLKSLKTDNRPEKSKCKPLWGKVFYLDLPSVTISEKLQKDIKDLGGRVEEFLSKDISYLISNKKEAKFAQTLG

UniProt accession no.

Q9UBU7

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DBF4(10926)

General description

Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at ′Ser-40′ and ′Ser-53′ and then is involved in regulating the initiation of DNA replication during cell cycle.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DBF4 (Q9UBU7).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

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