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SAB5702224

Sigma-Aldrich

Anti-NFAT2 Antibody, clone 4I9P10, Rabbit Monoclonal

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Synonym(s):
NF-ATC,NF-ATc1.2,NFAT2,NFATc,NFATC1

biological source

rabbit

Quality Level

100

material

colorless

clone

4I9P10, monoclonal

form

liquid

mol wt

110 kDa

species reactivity

mouse, mouse

concentration

1 mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

PSSPSPPLPPATQEPTCLQPCSPACPPATGRPQHLPSTVRRDESPTAGPRLLPEVHEDGSPNLAPIPVTVKREPEELDQLYLDDVNEIIRNDLSSTSTHS

UniProt accession no.

O95644

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NFATC1(4772)

General description

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 844-943 of human NFAT2 (O95644).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Regulatory Information

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