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Merck
CN

SAB5702251

Anti-YKL-40/CHI3L1 Antibody, clone 7T1R3, Rabbit Monoclonal

Synonym(s):

CHI3L1,ASRT7,CGP-39,GP-39,GP39,HC-gp39,HCGP-3P,YKL-40,YKL40,YYL-40,hCGP-39

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

material

colorless

clone

7T1R3, monoclonal

form

liquid

mol wt

30-43 kDa

species reactivity

mouse, mouse

concentration

1.00 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:1000

color

colorless

isotype

IgG

immunogen sequence

PGRFTKEAGTLAYYEICDFLRGATVHRILGQQVPYATKGNQWVGYDDQESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQDLRFPLTNAIKDALAAT

UniProt accession no.

P36222

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CHI3L1(1116)

General description

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 284-383 of human YKL-40/CHI3L1 (NP_001267.2).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IF/ICC

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H317,H411

Hazard Classifications

Aquatic Chronic 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Regulatory Information

常规特殊物品
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