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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
2T1J7, monoclonal
Application:
western blot
Species reactivity:
human, rat, rat
Citations:
Technique(s):
western blot: 1:500 - 1:1000
Uniprot accession no.:
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
2T1J7, monoclonal
form
liquid
mol wt
11 kDa
species reactivity
human, rat, rat
concentration
1 mg/mL
technique(s)
western blot: 1:500 - 1:1000
color
colorless
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... BGLAP(632)
Application
WB
General description
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
Immunogen
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant protein of Human BGLAP.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Skin Sens. 1
Storage Class
10 - Combustible liquids
wgk
WGK 3
Regulatory Information
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