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Merck
CN

SAB5702285

Anti-MRP1/ABCC1 Antibody, clone 0J6M2, Rabbit Monoclonal

Synonym(s):

ABC29, ABCC, GS-X, MRP, MRP1

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
0J6M2, monoclonal
Application:
immunohistochemistry
western blot
Species reactivity:
human, rat, rat
Citations:
Technique(s):
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:1000
Uniprot accession no.:
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biological source

rabbit

conjugate

unconjugated

material

colorless

clone

0J6M2, monoclonal

form

liquid

mol wt

200-250 kDa

species reactivity

human, rat, rat

concentration

1.00 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:1000

color

colorless

isotype

IgG

immunogen sequence

ESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKS

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... ABCC1(4363)

Application

WB, IHC

General description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]

Immunogen

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 210-304 of human MRP1/ABCC1 (NP_004987.2).

pictograms

Exclamation markEnvironment

signalword

Warning

hcodes

Hazard Classifications

Aquatic Chronic 2 - Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk

WGK 3

Regulatory Information

常规特殊物品
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