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Merck
CN

SAB5702306

Sigma-Aldrich

Anti-HEC1/NDC80 Antibody, clone 4W2Y2, Rabbit Monoclonal

Synonym(s):

HEC, HEC1, HsHec1, KNTC2, TID3, hsNDC80

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

material

colorless

clone

4W2Y2, monoclonal

form

liquid

mol wt

76 kDa

species reactivity

human

concentration

0.16 mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

ESTVNQGLSEAMNELDAVQREYQLVVQTTTEERRKVGNNLQRLLEMVATHVGSVEKHLEEQIAKVDREYEECMSEDLSENIKEIRDKYEKKATLIKSSEE

UniProt accession no.

O14777

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NDC80(10403)

General description

This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 543-642 of human HEC1/NDC80 (O14777).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Regulatory Information

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