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Merck
CN

SAB5702321

Anti-LIS1 Antibody, clone 9O6X3, Rabbit Monoclonal

Synonym(s):

LIS1, LIS2, MDCR, MDS, NudF, PAFAH

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
rat, human
Conjugate:
unconjugated
Application:
IF, IP, WB
Citations:
-
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biological source

rabbit

Quality Segment

conjugate

unconjugated

material

colorless

clone

9O6X3, monoclonal

form

liquid

mol wt

47 kDa

species reactivity

rat, human

concentration

0.6 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200, immunoprecipitation (IP): 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPE

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PAFAH1B1(5048)

General description

This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LIS1 (P43034).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IF/ICC, IP


Storage Class

10 - Combustible liquids

wgk

WGK 1



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