SAB5702327
Anti-Cadherin-13 (CDH13) Antibody, clone 4Z8D1, Rabbit Monoclonal
Synonym(s):
CDHH, P105
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
rat, human
Conjugate:
unconjugated
Application:
IHC, WB
Citations:
-
biological source
rabbit
Quality Segment
conjugate
unconjugated
material
colorless
clone
4Z8D1, monoclonal
form
liquid
species reactivity
rat, human
concentration
3 mg/mL
technique(s)
immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
PHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVT
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CDH13(1012)
General description
This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011]
Immunogen
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 101-200 of human Cadherin-13 (CDH13) (P55290).
Application
WB, IHC
Storage Class
10 - Combustible liquids
wgk
WGK 1
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