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Merck
CN

SAB5702356

Anti-NADPH oxidase 4 (NOX4) Antibody, clone 6Q3U8, Rabbit Monoclonal

Synonym(s):

KOX, KOX-1, RENOX

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
6Q3U8, monoclonal
Application:
immunohistochemistry
western blot
Species reactivity:
human, mouse, rat
Citations:
Technique(s):
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000
Uniprot accession no.:
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biological source

rabbit

conjugate

unconjugated

material

colorless

clone

6Q3U8, monoclonal

form

liquid

mol wt

67 kDa

species reactivity

human, mouse, rat

concentration

1.37 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

LHNKFWQENRPDYVNIQLYLSQTDGIQKIIGEKYHALNSRLFIGRPRWKLLFDEIAKYNRGKTVGVFCCGPNSLSKTLHKLSNQNNSYGTRFEYNKESFS

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... NOX4(50507)

Application

WB, IHC

General description

This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 479-578 of human NADPH oxidase 4 (NOX4) (Q9NPH5).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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