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Merck
CN

SAB5702359

Anti-PFKM Antibody, clone 4Z7X1, Rabbit Monoclonal

Synonym(s):

ATP-PFK, GSD7, PFK-1, PFK1, PFKA, PFKX, PPP1R122

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
human, rat
Conjugate:
unconjugated
Application:
WB
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

4Z7X1, monoclonal

form

liquid

mol wt

90 kDa

species reactivity

human, rat

concentration

3 mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

FVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEA

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PFKM(5213)

General description

Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Fructose 6 Phosphate Kinase (P08237).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB


Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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Global Trade Item Number

SKUGTIN
SAB5702359-100UL04065270695055