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Merck
CN

SAB5702371

Anti-HTRA2 Antibody, clone 4H8C4, Rabbit Monoclonal

Synonym(s):

MGCA8, OMI, PARK13, PRSS25

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
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color

colorless

biological source

rabbit

conjugate

unconjugated

material

colorless

clone

4H8C4, monoclonal

form

liquid

mol wt

36 kDa

species reactivity

rat, human, rat

concentration

0.48 mg/mL

technique(s)

western blot: 1:500 - 1:2000

isotype

IgG

immunogen sequence

GTRSRAWLAVALGAGGAVLLLLWGGGRGPPAVLAAVPSPPPASPRSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPISNGSGFVVAADGLIVTNAHVV

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... HTRA2(27429)

Application

WB

General description

This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human HTRA2 (O43464).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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