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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
color
colorless
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
4H8C4, monoclonal
form
liquid
mol wt
36 kDa
species reactivity
rat, human, rat
concentration
0.48 mg/mL
technique(s)
western blot: 1:500 - 1:2000
isotype
IgG
immunogen sequence
GTRSRAWLAVALGAGGAVLLLLWGGGRGPPAVLAAVPSPPPASPRSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPISNGSGFVVAADGLIVTNAHVV
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... HTRA2(27429)
Application
WB
General description
This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human HTRA2 (O43464).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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